Package: modACDC Title: Association of Covariance for Detecting Differential Co-Expression Version: 2.0.1 Authors@R: c(person(given = "Katelyn", family = "Queen", email = "kjqueen@usc.edu", role = c("aut", "cre", "cph"), comment = c(ORCID = "0000-0002-8070-3042")), person(given = "Joshua", family = "Millstein", , email = "joshua.millstein@usc.edu", role = c("aut","cph"), comment = c(ORCID = "0000-0001-7961-8943"))) Maintainer: Katelyn Queen Description: A series of functions to implement association of covariance for detecting differential co-expression (ACDC), a novel approach for detection of differential co-expression that simultaneously accommodates multiple phenotypes or exposures with binary, ordinal, or continuous data types. Users can use the default method which identifies modules by Partition or may supply their own modules. Also included are functions to choose an information loss criterion (ILC) for Partition using OmicS-data-based Complex trait Analysis (OSCA) and Genome-wide Complex trait Analysis (GCTA). The manuscript describing these methods is as follows: Queen K, Nguyen MN, Gilliland F, Chun S, Raby BA, Millstein J. "ACDC: a general approach for detecting phenotype or exposure associated co-expression" (2023) . License: MIT + file LICENSE URL: https://github.com/USCbiostats/ACDC Depends: R (>= 4.1.0) Imports: CCP, data.table, doParallel, foreach, genieclust, genio, ggplot2, partition, parallel, tibble, tidyr, tools, utils Suggests: CCA Encoding: UTF-8 Roxygen: list(markdown = TRUE) RoxygenNote: 7.2.3 Config/pak/sysreqs: libicu-dev libx11-dev Repository: https://uscbiostats.r-universe.dev Date/Publication: 2024-04-09 17:59:27 UTC RemoteUrl: https://github.com/uscbiostats/acdc RemoteRef: HEAD RemoteSha: 4d535285fc8394f0691f91d2a860ef4a14b85a8f NeedsCompilation: no Packaged: 2026-06-07 08:41:17 UTC; root Author: Katelyn Queen [aut, cre, cph] (ORCID: ), Joshua Millstein [aut, cph] (ORCID: )